CovidFranceV1, Main, Exploration, bibRecord, 001314

Cluster of Coronavirus Disease 2019 (COVID-19) in the French Alps, February 2020.

Identifieur interne : 001314 ( Main/Exploration ); précédent : 001313; suivant : 001315

Cluster of Coronavirus Disease 2019 (COVID-19) in the French Alps, February 2020.

Auteurs : Kostas Danis [France] ; Olivier Epaulard [France] ; Thomas Bénet [France] ; Alexandre Gaymard [France] ; Séphora Campoy [France] ; Elisabeth Botelho-Nevers [France] ; Maude Bouscambert-Duchamp [France] ; Guillaume Spaccaferri [France] ; Florence Ader [France] ; Alexandra Mailles [France] ; Zoubida Boudalaa [France] ; Violaine Tolsma [France] ; Julien Berra [France] ; Sophie Vaux [France] ; Emmanuel Forestier [France] ; Caroline Landelle [France] ; Erica Fougere [France] ; Alexandra Thabuis [France] ; Philippe Berthelot [France] ; Raphael Veil [France] ; Daniel Levy-Bruhl [France] ; Christian Chidiac [France] ; Bruno Lina [France] ; Bruno Coignard [France] ; Christine Saura [France]

Source :

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1537-6591 ] ; 2020.

RBID : pubmed:32277759

Descripteurs français

KwdFr :
- Adulte d'âge moyen (MeSH), Analyse de regroupements (MeSH), Betacoronavirus (isolement et purification), Femelle (MeSH), France (MeSH), Humains (MeSH), Infections à coronavirus (virologie), Pandémies (MeSH), Pneumopathie virale (virologie), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Tests sérologiques (méthodes), Études rétrospectives (MeSH).
MESH :
- isolement et purification : Betacoronavirus.
- méthodes : Tests sérologiques.
- virologie : Infections à coronavirus, Pneumopathie virale.
- Adulte d'âge moyen, Analyse de regroupements, Femelle, France, Humains, Pandémies, Sujet âgé, Sujet âgé de 80 ans ou plus, Études rétrospectives.
Wicri :
- geographic : France.

English descriptors

KwdEn :
- Aged (MeSH), Aged, 80 and over (MeSH), Betacoronavirus (isolation & purification), Cluster Analysis (MeSH), Coronavirus Infections (virology), Female (MeSH), France (MeSH), Humans (MeSH), Middle Aged (MeSH), Pandemics (MeSH), Pneumonia, Viral (virology), Retrospective Studies (MeSH), Serologic Tests (methods).
MESH :
- geographic : France.
- isolation & purification : Betacoronavirus.
- methods : Serologic Tests.
- virology : Coronavirus Infections, Pneumonia, Viral.
- Aged, Aged, 80 and over, Cluster Analysis, Female, Humans, Middle Aged, Pandemics, Retrospective Studies.

Abstract

BACKGROUND

On 7 February 2020, French Health authorities were informed of a confirmed case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an Englishman infected in Singapore who had recently stayed in a chalet in the French Alps. We conducted an investigation to identify secondary cases and interrupt transmission.

METHODS

We defined as a confirmed case a person linked to the chalet with a positive reverse-transcription polymerase chain reaction sample for SARS-CoV-2.

RESULTS

The index case stayed 4 days in the chalet with 10 English tourists and a family of 5 French residents; SARS-CoV-2 was detected in 5 individuals in France, 6 in England (including the index case), and 1 in Spain (overall attack rate in the chalet: 75%). One pediatric case, with picornavirus and influenza A coinfection, visited 3 different schools while symptomatic. One case was asymptomatic, with similar viral load as that of a symptomatic case. Seven days after the first cases were diagnosed, 1 tertiary case was detected in a symptomatic patient with from the chalet a positive endotracheal aspirate; all previous and concurrent nasopharyngeal specimens were negative. Additionally, 172 contacts were monitored; all contacts tested for SARS-CoV-2 (N = 73) were negative.

CONCLUSIONS

The occurrence in this cluster of 1 asymptomatic case with similar viral load as a symptomatic patient suggests transmission potential of asymptomatic individuals. The fact that an infected child did not transmit the disease despite close interactions within schools suggests potential different transmission dynamics in children. Finally, the dissociation between upper and lower respiratory tract results underscores the need for close monitoring of the clinical evolution of suspected cases of coronavirus disease 2019.

DOI: 10.1093/cid/ciaa424
PubMed: 32277759
PubMed Central: PMC7184384

Affiliations:

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Le document en format XML

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<author><name sortKey="Botelho Nevers, Elisabeth" sort="Botelho Nevers, Elisabeth" uniqKey="Botelho Nevers E" first="Elisabeth" last="Botelho-Nevers">Elisabeth Botelho-Nevers</name>
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<author><name sortKey="Bouscambert Duchamp, Maude" sort="Bouscambert Duchamp, Maude" uniqKey="Bouscambert Duchamp M" first="Maude" last="Bouscambert-Duchamp">Maude Bouscambert-Duchamp</name>
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<author><name sortKey="Ader, Florence" sort="Ader, Florence" uniqKey="Ader F" first="Florence" last="Ader">Florence Ader</name>
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<author><name sortKey="Mailles, Alexandra" sort="Mailles, Alexandra" uniqKey="Mailles A" first="Alexandra" last="Mailles">Alexandra Mailles</name>
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<author><name sortKey="Boudalaa, Zoubida" sort="Boudalaa, Zoubida" uniqKey="Boudalaa Z" first="Zoubida" last="Boudalaa">Zoubida Boudalaa</name>
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<author><name sortKey="Tolsma, Violaine" sort="Tolsma, Violaine" uniqKey="Tolsma V" first="Violaine" last="Tolsma">Violaine Tolsma</name>
<affiliation wicri:level="3"><nlm:affiliation>Infectious Diseases Unit, Centre Hospitalier Annecy Genevois, Annecy, France.</nlm:affiliation>
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<author><name sortKey="Berra, Julien" sort="Berra, Julien" uniqKey="Berra J" first="Julien" last="Berra">Julien Berra</name>
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<author><name sortKey="Vaux, Sophie" sort="Vaux, Sophie" uniqKey="Vaux S" first="Sophie" last="Vaux">Sophie Vaux</name>
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<country xml:lang="fr">France</country>
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<author><name sortKey="Forestier, Emmanuel" sort="Forestier, Emmanuel" uniqKey="Forestier E" first="Emmanuel" last="Forestier">Emmanuel Forestier</name>
<affiliation wicri:level="3"><nlm:affiliation>Infectious Disease Department, Centre Hospitalier Metropole Savoie, Chambery, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Infectious Disease Department, Centre Hospitalier Metropole Savoie, Chambery</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
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<settlement type="city">Chambéry</settlement>
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</author>
<author><name sortKey="Landelle, Caroline" sort="Landelle, Caroline" uniqKey="Landelle C" first="Caroline" last="Landelle">Caroline Landelle</name>
<affiliation wicri:level="3"><nlm:affiliation>Service d'Hygiène Hospitalière et de Gestion des Risques, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service d'Hygiène Hospitalière et de Gestion des Risques, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Grenoble</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="4"><nlm:affiliation>Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques, Applications, Grenoble, Unité Mixte de Recherche 5525 (TIMC-IMAG UMR5525), CNRS, Université Grenoble Alpes, Grenoble, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques, Applications, Grenoble, Unité Mixte de Recherche 5525 (TIMC-IMAG UMR5525), CNRS, Université Grenoble Alpes, Grenoble</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
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<orgName type="university">Université Grenoble-Alpes</orgName>
</affiliation>
</author>
<author><name sortKey="Fougere, Erica" sort="Fougere, Erica" uniqKey="Fougere E" first="Erica" last="Fougere">Erica Fougere</name>
<affiliation wicri:level="3"><nlm:affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Thabuis, Alexandra" sort="Thabuis, Alexandra" uniqKey="Thabuis A" first="Alexandra" last="Thabuis">Alexandra Thabuis</name>
<affiliation wicri:level="3"><nlm:affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Berthelot, Philippe" sort="Berthelot, Philippe" uniqKey="Berthelot P" first="Philippe" last="Berthelot">Philippe Berthelot</name>
<affiliation wicri:level="3"><nlm:affiliation>Infectious Diseases Department, University Hospital of Saint-Etienne, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Infectious Diseases Department, University Hospital of Saint-Etienne, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Groupe Immunité des Muqueuses et Agents Pathogènes, Université Jean Monnet, Université de Lyon, St-Etienne, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Groupe Immunité des Muqueuses et Agents Pathogènes, Université Jean Monnet, Université de Lyon, St-Etienne</wicri:regionArea>
<wicri:noRegion>St-Etienne</wicri:noRegion>
<wicri:noRegion>St-Etienne</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Veil, Raphael" sort="Veil, Raphael" uniqKey="Veil R" first="Raphael" last="Veil">Raphael Veil</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Emergency Operations Center, French Ministry of Health, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Public Health Emergency Operations Center, French Ministry of Health, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Levy Bruhl, Daniel" sort="Levy Bruhl, Daniel" uniqKey="Levy Bruhl D" first="Daniel" last="Levy-Bruhl">Daniel Levy-Bruhl</name>
<affiliation wicri:level="1"><nlm:affiliation>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice</wicri:regionArea>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chidiac, Christian" sort="Chidiac, Christian" uniqKey="Chidiac C" first="Christian" last="Chidiac">Christian Chidiac</name>
<affiliation wicri:level="3"><nlm:affiliation>Infectious and Tropical Disease Department, Croix-Rousse Hospital, University Hospital of Lyon, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Infectious and Tropical Disease Department, Croix-Rousse Hospital, University Hospital of Lyon, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="4"><nlm:affiliation>Maladies Infectieuses et Tropicales, Université Claude Bernard Lyon 1 (UCBL1), Unité de formation et de recherche (UFR) Lyon Sud-Charles Mérieux, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Maladies Infectieuses et Tropicales, Université Claude Bernard Lyon 1 (UCBL1), Unité de formation et de recherche (UFR) Lyon Sud-Charles Mérieux, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
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<orgName type="university">Université Claude Bernard Lyon 1</orgName>
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<author><name sortKey="Lina, Bruno" sort="Lina, Bruno" uniqKey="Lina B" first="Bruno" last="Lina">Bruno Lina</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Virology, Infective Agents Institute, National Reference Center for Respiratory Viruses North Hospital Network, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Virology, Infective Agents Institute, National Reference Center for Respiratory Viruses North Hospital Network, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Coignard, Bruno" sort="Coignard, Bruno" uniqKey="Coignard B" first="Bruno" last="Coignard">Bruno Coignard</name>
<affiliation wicri:level="1"><nlm:affiliation>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice</wicri:regionArea>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Saura, Christine" sort="Saura, Christine" uniqKey="Saura C" first="Christine" last="Saura">Christine Saura</name>
<affiliation wicri:level="3"><nlm:affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2020">2020</date>
<idno type="RBID">pubmed:32277759</idno>
<idno type="pmid">32277759</idno>
<idno type="doi">10.1093/cid/ciaa424</idno>
<idno type="pmc">PMC7184384</idno>
<idno type="wicri:Area/Main/Corpus">001759</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Cluster of Coronavirus Disease 2019 (COVID-19) in the French Alps, February 2020.</title>
<author><name sortKey="Danis, Kostas" sort="Danis, Kostas" uniqKey="Danis K" first="Kostas" last="Danis">Kostas Danis</name>
<affiliation wicri:level="1"><nlm:affiliation>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice</wicri:regionArea>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Epaulard, Olivier" sort="Epaulard, Olivier" uniqKey="Epaulard O" first="Olivier" last="Epaulard">Olivier Epaulard</name>
<affiliation wicri:level="3"><nlm:affiliation>Infectious Diseases Department, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Infectious Diseases Department, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Grenoble</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="4"><nlm:affiliation>Fédération d'infectiologie multidisciplinaire de l'Arc Alpin, Université Grenoble Alpes, Grenoble, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Fédération d'infectiologie multidisciplinaire de l'Arc Alpin, Université Grenoble Alpes, Grenoble</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Grenoble</settlement>
</placeName>
<orgName type="university">Université Grenoble-Alpes</orgName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Unité Mixte de Recherche 5075 (UMR 5075), Institut de biologie structurale, Grenoble, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Unité Mixte de Recherche 5075 (UMR 5075), Institut de biologie structurale, Grenoble</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Grenoble</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Benet, Thomas" sort="Benet, Thomas" uniqKey="Benet T" first="Thomas" last="Bénet">Thomas Bénet</name>
<affiliation wicri:level="3"><nlm:affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gaymard, Alexandre" sort="Gaymard, Alexandre" uniqKey="Gaymard A" first="Alexandre" last="Gaymard">Alexandre Gaymard</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Virology, Infective Agents Institute, National Reference Center for Respiratory Viruses North Hospital Network, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Virology, Infective Agents Institute, National Reference Center for Respiratory Viruses North Hospital Network, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Campoy, Sephora" sort="Campoy, Sephora" uniqKey="Campoy S" first="Séphora" last="Campoy">Séphora Campoy</name>
<affiliation wicri:level="3"><nlm:affiliation>Regional Health Agency of Auvergne Rhône Alpes, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Regional Health Agency of Auvergne Rhône Alpes, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Botelho Nevers, Elisabeth" sort="Botelho Nevers, Elisabeth" uniqKey="Botelho Nevers E" first="Elisabeth" last="Botelho-Nevers">Elisabeth Botelho-Nevers</name>
<affiliation wicri:level="3"><nlm:affiliation>Infectious Diseases Department, University Hospital of Saint-Etienne, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Infectious Diseases Department, University Hospital of Saint-Etienne, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Groupe Immunité des Muqueuses et Agents Pathogènes, Université Jean Monnet, Université de Lyon, St-Etienne, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Groupe Immunité des Muqueuses et Agents Pathogènes, Université Jean Monnet, Université de Lyon, St-Etienne</wicri:regionArea>
<wicri:noRegion>St-Etienne</wicri:noRegion>
<wicri:noRegion>St-Etienne</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bouscambert Duchamp, Maude" sort="Bouscambert Duchamp, Maude" uniqKey="Bouscambert Duchamp M" first="Maude" last="Bouscambert-Duchamp">Maude Bouscambert-Duchamp</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Virology, Infective Agents Institute, National Reference Center for Respiratory Viruses North Hospital Network, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Virology, Infective Agents Institute, National Reference Center for Respiratory Viruses North Hospital Network, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Spaccaferri, Guillaume" sort="Spaccaferri, Guillaume" uniqKey="Spaccaferri G" first="Guillaume" last="Spaccaferri">Guillaume Spaccaferri</name>
<affiliation wicri:level="3"><nlm:affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ader, Florence" sort="Ader, Florence" uniqKey="Ader F" first="Florence" last="Ader">Florence Ader</name>
<affiliation wicri:level="3"><nlm:affiliation>Infectious and Tropical Disease Department, Croix-Rousse Hospital, University Hospital of Lyon, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Infectious and Tropical Disease Department, Croix-Rousse Hospital, University Hospital of Lyon, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mailles, Alexandra" sort="Mailles, Alexandra" uniqKey="Mailles A" first="Alexandra" last="Mailles">Alexandra Mailles</name>
<affiliation wicri:level="1"><nlm:affiliation>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice</wicri:regionArea>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Boudalaa, Zoubida" sort="Boudalaa, Zoubida" uniqKey="Boudalaa Z" first="Zoubida" last="Boudalaa">Zoubida Boudalaa</name>
<affiliation wicri:level="3"><nlm:affiliation>Regional Health Agency of Auvergne Rhône Alpes, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Regional Health Agency of Auvergne Rhône Alpes, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tolsma, Violaine" sort="Tolsma, Violaine" uniqKey="Tolsma V" first="Violaine" last="Tolsma">Violaine Tolsma</name>
<affiliation wicri:level="3"><nlm:affiliation>Infectious Diseases Unit, Centre Hospitalier Annecy Genevois, Annecy, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Infectious Diseases Unit, Centre Hospitalier Annecy Genevois, Annecy</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Annecy</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Berra, Julien" sort="Berra, Julien" uniqKey="Berra J" first="Julien" last="Berra">Julien Berra</name>
<affiliation wicri:level="3"><nlm:affiliation>Regional Health Agency of Auvergne Rhône Alpes, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Regional Health Agency of Auvergne Rhône Alpes, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vaux, Sophie" sort="Vaux, Sophie" uniqKey="Vaux S" first="Sophie" last="Vaux">Sophie Vaux</name>
<affiliation wicri:level="1"><nlm:affiliation>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice</wicri:regionArea>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Forestier, Emmanuel" sort="Forestier, Emmanuel" uniqKey="Forestier E" first="Emmanuel" last="Forestier">Emmanuel Forestier</name>
<affiliation wicri:level="3"><nlm:affiliation>Infectious Disease Department, Centre Hospitalier Metropole Savoie, Chambery, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Infectious Disease Department, Centre Hospitalier Metropole Savoie, Chambery</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Chambéry</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Landelle, Caroline" sort="Landelle, Caroline" uniqKey="Landelle C" first="Caroline" last="Landelle">Caroline Landelle</name>
<affiliation wicri:level="3"><nlm:affiliation>Service d'Hygiène Hospitalière et de Gestion des Risques, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service d'Hygiène Hospitalière et de Gestion des Risques, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Grenoble</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="4"><nlm:affiliation>Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques, Applications, Grenoble, Unité Mixte de Recherche 5525 (TIMC-IMAG UMR5525), CNRS, Université Grenoble Alpes, Grenoble, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques, Applications, Grenoble, Unité Mixte de Recherche 5525 (TIMC-IMAG UMR5525), CNRS, Université Grenoble Alpes, Grenoble</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Grenoble</settlement>
</placeName>
<orgName type="university">Université Grenoble-Alpes</orgName>
</affiliation>
</author>
<author><name sortKey="Fougere, Erica" sort="Fougere, Erica" uniqKey="Fougere E" first="Erica" last="Fougere">Erica Fougere</name>
<affiliation wicri:level="3"><nlm:affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Thabuis, Alexandra" sort="Thabuis, Alexandra" uniqKey="Thabuis A" first="Alexandra" last="Thabuis">Alexandra Thabuis</name>
<affiliation wicri:level="3"><nlm:affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Berthelot, Philippe" sort="Berthelot, Philippe" uniqKey="Berthelot P" first="Philippe" last="Berthelot">Philippe Berthelot</name>
<affiliation wicri:level="3"><nlm:affiliation>Infectious Diseases Department, University Hospital of Saint-Etienne, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Infectious Diseases Department, University Hospital of Saint-Etienne, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Groupe Immunité des Muqueuses et Agents Pathogènes, Université Jean Monnet, Université de Lyon, St-Etienne, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Groupe Immunité des Muqueuses et Agents Pathogènes, Université Jean Monnet, Université de Lyon, St-Etienne</wicri:regionArea>
<wicri:noRegion>St-Etienne</wicri:noRegion>
<wicri:noRegion>St-Etienne</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Veil, Raphael" sort="Veil, Raphael" uniqKey="Veil R" first="Raphael" last="Veil">Raphael Veil</name>
<affiliation wicri:level="3"><nlm:affiliation>Public Health Emergency Operations Center, French Ministry of Health, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Public Health Emergency Operations Center, French Ministry of Health, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Levy Bruhl, Daniel" sort="Levy Bruhl, Daniel" uniqKey="Levy Bruhl D" first="Daniel" last="Levy-Bruhl">Daniel Levy-Bruhl</name>
<affiliation wicri:level="1"><nlm:affiliation>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice</wicri:regionArea>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chidiac, Christian" sort="Chidiac, Christian" uniqKey="Chidiac C" first="Christian" last="Chidiac">Christian Chidiac</name>
<affiliation wicri:level="3"><nlm:affiliation>Infectious and Tropical Disease Department, Croix-Rousse Hospital, University Hospital of Lyon, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Infectious and Tropical Disease Department, Croix-Rousse Hospital, University Hospital of Lyon, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="4"><nlm:affiliation>Maladies Infectieuses et Tropicales, Université Claude Bernard Lyon 1 (UCBL1), Unité de formation et de recherche (UFR) Lyon Sud-Charles Mérieux, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Maladies Infectieuses et Tropicales, Université Claude Bernard Lyon 1 (UCBL1), Unité de formation et de recherche (UFR) Lyon Sud-Charles Mérieux, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
<orgName type="university">Université Claude Bernard Lyon 1</orgName>
</affiliation>
</author>
<author><name sortKey="Lina, Bruno" sort="Lina, Bruno" uniqKey="Lina B" first="Bruno" last="Lina">Bruno Lina</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Virology, Infective Agents Institute, National Reference Center for Respiratory Viruses North Hospital Network, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Virology, Infective Agents Institute, National Reference Center for Respiratory Viruses North Hospital Network, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Coignard, Bruno" sort="Coignard, Bruno" uniqKey="Coignard B" first="Bruno" last="Coignard">Bruno Coignard</name>
<affiliation wicri:level="1"><nlm:affiliation>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice</wicri:regionArea>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Saura, Christine" sort="Saura, Christine" uniqKey="Saura C" first="Christine" last="Saura">Christine Saura</name>
<affiliation wicri:level="3"><nlm:affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</title>
<idno type="eISSN">1537-6591</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term>
<term>Aged, 80 and over (MeSH)</term>
<term>Betacoronavirus (isolation & purification)</term>
<term>Cluster Analysis (MeSH)</term>
<term>Coronavirus Infections (virology)</term>
<term>Female (MeSH)</term>
<term>France (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Pneumonia, Viral (virology)</term>
<term>Retrospective Studies (MeSH)</term>
<term>Serologic Tests (methods)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen (MeSH)</term>
<term>Analyse de regroupements (MeSH)</term>
<term>Betacoronavirus (isolement et purification)</term>
<term>Femelle (MeSH)</term>
<term>France (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Pandémies (MeSH)</term>
<term>Pneumopathie virale (virologie)</term>
<term>Sujet âgé (MeSH)</term>
<term>Sujet âgé de 80 ans ou plus (MeSH)</term>
<term>Tests sérologiques (méthodes)</term>
<term>Études rétrospectives (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>France</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Serologic Tests</term>
</keywords>
<keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Tests sérologiques</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Cluster Analysis</term>
<term>Female</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Pandemics</term>
<term>Retrospective Studies</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Analyse de regroupements</term>
<term>Femelle</term>
<term>France</term>
<term>Humains</term>
<term>Pandémies</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Études rétrospectives</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>France</term>
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<front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b>
</p>
<p>On 7 February 2020, French Health authorities were informed of a confirmed case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an Englishman infected in Singapore who had recently stayed in a chalet in the French Alps. We conducted an investigation to identify secondary cases and interrupt transmission.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>We defined as a confirmed case a person linked to the chalet with a positive reverse-transcription polymerase chain reaction sample for SARS-CoV-2.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>The index case stayed 4 days in the chalet with 10 English tourists and a family of 5 French residents; SARS-CoV-2 was detected in 5 individuals in France, 6 in England (including the index case), and 1 in Spain (overall attack rate in the chalet: 75%). One pediatric case, with picornavirus and influenza A coinfection, visited 3 different schools while symptomatic. One case was asymptomatic, with similar viral load as that of a symptomatic case. Seven days after the first cases were diagnosed, 1 tertiary case was detected in a symptomatic patient with from the chalet a positive endotracheal aspirate; all previous and concurrent nasopharyngeal specimens were negative. Additionally, 172 contacts were monitored; all contacts tested for SARS-CoV-2 (N = 73) were negative.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>The occurrence in this cluster of 1 asymptomatic case with similar viral load as a symptomatic patient suggests transmission potential of asymptomatic individuals. The fact that an infected child did not transmit the disease despite close interactions within schools suggests potential different transmission dynamics in children. Finally, the dissociation between upper and lower respiratory tract results underscores the need for close monitoring of the clinical evolution of suspected cases of coronavirus disease 2019.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32277759</PMID>
<DateCompleted><Year>2020</Year>
<Month>08</Month>
<Day>10</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>08</Month>
<Day>10</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1537-6591</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>71</Volume>
<Issue>15</Issue>
<PubDate><Year>2020</Year>
<Month>07</Month>
<Day>28</Day>
</PubDate>
</JournalIssue>
<Title>Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</Title>
<ISOAbbreviation>Clin. Infect. Dis.</ISOAbbreviation>
</Journal>
<ArticleTitle>Cluster of Coronavirus Disease 2019 (COVID-19) in the French Alps, February 2020.</ArticleTitle>
<Pagination><MedlinePgn>825-832</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1093/cid/ciaa424</ELocationID>
<Abstract><AbstractText Label="BACKGROUND">On 7 February 2020, French Health authorities were informed of a confirmed case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an Englishman infected in Singapore who had recently stayed in a chalet in the French Alps. We conducted an investigation to identify secondary cases and interrupt transmission.</AbstractText>
<AbstractText Label="METHODS">We defined as a confirmed case a person linked to the chalet with a positive reverse-transcription polymerase chain reaction sample for SARS-CoV-2.</AbstractText>
<AbstractText Label="RESULTS">The index case stayed 4 days in the chalet with 10 English tourists and a family of 5 French residents; SARS-CoV-2 was detected in 5 individuals in France, 6 in England (including the index case), and 1 in Spain (overall attack rate in the chalet: 75%). One pediatric case, with picornavirus and influenza A coinfection, visited 3 different schools while symptomatic. One case was asymptomatic, with similar viral load as that of a symptomatic case. Seven days after the first cases were diagnosed, 1 tertiary case was detected in a symptomatic patient with from the chalet a positive endotracheal aspirate; all previous and concurrent nasopharyngeal specimens were negative. Additionally, 172 contacts were monitored; all contacts tested for SARS-CoV-2 (N = 73) were negative.</AbstractText>
<AbstractText Label="CONCLUSIONS">The occurrence in this cluster of 1 asymptomatic case with similar viral load as a symptomatic patient suggests transmission potential of asymptomatic individuals. The fact that an infected child did not transmit the disease despite close interactions within schools suggests potential different transmission dynamics in children. Finally, the dissociation between upper and lower respiratory tract results underscores the need for close monitoring of the clinical evolution of suspected cases of coronavirus disease 2019.</AbstractText>
<CopyrightInformation>© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Danis</LastName>
<ForeName>Kostas</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Epaulard</LastName>
<ForeName>Olivier</ForeName>
<Initials>O</Initials>
<AffiliationInfo><Affiliation>Infectious Diseases Department, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Fédération d'infectiologie multidisciplinaire de l'Arc Alpin, Université Grenoble Alpes, Grenoble, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Unité Mixte de Recherche 5075 (UMR 5075), Institut de biologie structurale, Grenoble, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bénet</LastName>
<ForeName>Thomas</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gaymard</LastName>
<ForeName>Alexandre</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Virology, Infective Agents Institute, National Reference Center for Respiratory Viruses North Hospital Network, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Campoy</LastName>
<ForeName>Séphora</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Regional Health Agency of Auvergne Rhône Alpes, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Botelho-Nevers</LastName>
<ForeName>Elisabeth</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Infectious Diseases Department, University Hospital of Saint-Etienne, Lyon, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Groupe Immunité des Muqueuses et Agents Pathogènes, Université Jean Monnet, Université de Lyon, St-Etienne, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bouscambert-Duchamp</LastName>
<ForeName>Maude</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Virology, Infective Agents Institute, National Reference Center for Respiratory Viruses North Hospital Network, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Spaccaferri</LastName>
<ForeName>Guillaume</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ader</LastName>
<ForeName>Florence</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Infectious and Tropical Disease Department, Croix-Rousse Hospital, University Hospital of Lyon, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mailles</LastName>
<ForeName>Alexandra</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Boudalaa</LastName>
<ForeName>Zoubida</ForeName>
<Initials>Z</Initials>
<AffiliationInfo><Affiliation>Regional Health Agency of Auvergne Rhône Alpes, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tolsma</LastName>
<ForeName>Violaine</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Infectious Diseases Unit, Centre Hospitalier Annecy Genevois, Annecy, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Berra</LastName>
<ForeName>Julien</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Regional Health Agency of Auvergne Rhône Alpes, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vaux</LastName>
<ForeName>Sophie</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Forestier</LastName>
<ForeName>Emmanuel</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Infectious Disease Department, Centre Hospitalier Metropole Savoie, Chambery, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Landelle</LastName>
<ForeName>Caroline</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Service d'Hygiène Hospitalière et de Gestion des Risques, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques, Applications, Grenoble, Unité Mixte de Recherche 5525 (TIMC-IMAG UMR5525), CNRS, Université Grenoble Alpes, Grenoble, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fougere</LastName>
<ForeName>Erica</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Thabuis</LastName>
<ForeName>Alexandra</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Berthelot</LastName>
<ForeName>Philippe</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Infectious Diseases Department, University Hospital of Saint-Etienne, Lyon, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Groupe Immunité des Muqueuses et Agents Pathogènes, Université Jean Monnet, Université de Lyon, St-Etienne, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Veil</LastName>
<ForeName>Raphael</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Public Health Emergency Operations Center, French Ministry of Health, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Levy-Bruhl</LastName>
<ForeName>Daniel</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chidiac</LastName>
<ForeName>Christian</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Infectious and Tropical Disease Department, Croix-Rousse Hospital, University Hospital of Lyon, Lyon, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Maladies Infectieuses et Tropicales, Université Claude Bernard Lyon 1 (UCBL1), Unité de formation et de recherche (UFR) Lyon Sud-Charles Mérieux, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lina</LastName>
<ForeName>Bruno</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Department of Virology, Infective Agents Institute, National Reference Center for Respiratory Viruses North Hospital Network, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Coignard</LastName>
<ForeName>Bruno</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>French National Public Health Agency, Department of Infectious Diseases, Saint-Maurice, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Saura</LastName>
<ForeName>Christine</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>French National Public Health Agency, Auvergne-Rhône-Alpes Regional Office, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><CollectiveName>Investigation Team</CollectiveName>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Clin Infect Dis</MedlineTA>
<NlmUniqueID>9203213</NlmUniqueID>
<ISSNLinking>1058-4838</ISSNLinking>
</MedlineJournalInfo>
<SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName>
<SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName>
</SupplMeshList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016000" MajorTopicYN="N">Cluster Analysis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005602" MajorTopicYN="N" Type="Geographic">France</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012698" MajorTopicYN="N">Serologic Tests</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">COVID-19</Keyword>
<Keyword MajorTopicYN="Y">SARS-CoV-2</Keyword>
<Keyword MajorTopicYN="Y">cluster</Keyword>
<Keyword MajorTopicYN="Y">coronavirus</Keyword>
<Keyword MajorTopicYN="Y">infection</Keyword>
</KeywordList>
<InvestigatorList><Investigator ValidYN="Y"><LastName>Brottet</LastName>
<ForeName>Elise</ForeName>
<Initials>E</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Casamatta</LastName>
<ForeName>Delphine</ForeName>
<Initials>D</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Gallien</LastName>
<ForeName>Yves</ForeName>
<Initials>Y</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>George</LastName>
<ForeName>Scarlett</ForeName>
<Initials>S</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Viriot</LastName>
<ForeName>Delphine</ForeName>
<Initials>D</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Ait Belghiti</LastName>
<ForeName>Fatima</ForeName>
<Initials>F</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bernard-Stoecklin</LastName>
<ForeName>Sibylle</ForeName>
<Initials>S</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Desenclos</LastName>
<ForeName>Jean-Claude</ForeName>
<Initials>JC</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Giese</LastName>
<ForeName>Coralie</ForeName>
<Initials>C</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Ghislain</LastName>
<ForeName>Didier</ForeName>
<Initials>D</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Gounon</LastName>
<ForeName>Magali</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Grangeret</LastName>
<ForeName>Nathalie</ForeName>
<Initials>N</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Marie</LastName>
<ForeName>Cécile</ForeName>
<Initials>C</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Morel</LastName>
<ForeName>Bruno</ForeName>
<Initials>B</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Deher</LastName>
<ForeName>Muriel</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Ronnaux Baron</LastName>
<ForeName>Anne-Sophie</ForeName>
<Initials>AS</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Courbis</LastName>
<ForeName>Geneviève</ForeName>
<Initials>G</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Ragozin</LastName>
<ForeName>Nathalie</ForeName>
<Initials>N</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Wolska</LastName>
<ForeName>Monika</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Serange</LastName>
<ForeName>Eric</ForeName>
<Initials>E</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Mercatello</LastName>
<ForeName>Delphine</ForeName>
<Initials>D</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Aiouaz</LastName>
<ForeName>Soraya</ForeName>
<Initials>S</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Valette</LastName>
<ForeName>Martine</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Frobert</LastName>
<ForeName>Emilie</ForeName>
<Initials>E</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Josset</LastName>
<ForeName>Laurence</ForeName>
<Initials>L</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Escuret</LastName>
<ForeName>Vanessa</ForeName>
<Initials>V</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Morfin</LastName>
<ForeName>Florence</ForeName>
<Initials>F</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Billaud</LastName>
<ForeName>Geneviève</ForeName>
<Initials>G</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Blanc</LastName>
<ForeName>Myriam</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Arata-Bardet</LastName>
<ForeName>Julie</ForeName>
<Initials>J</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Froidure</LastName>
<ForeName>Marie</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Le Maréchal</LastName>
<ForeName>Marion</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Pavese</LastName>
<ForeName>Patricia</ForeName>
<Initials>P</Initials>
</Investigator>
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<ForeName>Isabelle</ForeName>
<Initials>I</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Becker</LastName>
<ForeName>Agathe</ForeName>
<Initials>A</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Chauvelot</LastName>
<ForeName>Pierre</ForeName>
<Initials>P</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Conrad</LastName>
<ForeName>Anne</ForeName>
<Initials>A</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Ferry</LastName>
<ForeName>Tristan</ForeName>
<Initials>T</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Miailhes</LastName>
<ForeName>Patrick</ForeName>
<Initials>P</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Perpoint</LastName>
<ForeName>Thomas</ForeName>
<Initials>T</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Pouderoux</LastName>
<ForeName>Cécile</ForeName>
<Initials>C</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Roux</LastName>
<ForeName>Sandrine</ForeName>
<Initials>S</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Valour</LastName>
<ForeName>Florent</ForeName>
<Initials>F</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Lutz</LastName>
<ForeName>Marie-France</ForeName>
<Initials>MF</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Pouvaret</LastName>
<ForeName>Anne</ForeName>
<Initials>A</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Vitrat</LastName>
<ForeName>Virginie</ForeName>
<Initials>V</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Maillet</LastName>
<ForeName>Mylène</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Janssen</LastName>
<ForeName>Cécile</ForeName>
<Initials>C</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Piet</LastName>
<ForeName>Emilie</ForeName>
<Initials>E</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bosch</LastName>
<ForeName>Alexie</ForeName>
<Initials>A</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Destrem</LastName>
<ForeName>Anne-Laure</ForeName>
<Initials>AL</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Isnard</LastName>
<ForeName>Margaux</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Challan-Belval</LastName>
<ForeName>Thibault</ForeName>
<Initials>T</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Wackenheim</LastName>
<ForeName>Chloe</ForeName>
<Initials>C</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Couturier</LastName>
<ForeName>Alice</ForeName>
<Initials>A</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Gheno</LastName>
<ForeName>Gael</ForeName>
<Initials>G</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Roupioz</LastName>
<ForeName>Thierry</ForeName>
<Initials>T</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Lucet</LastName>
<ForeName>Nicolas</ForeName>
<Initials>N</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Ayouni</LastName>
<ForeName>Stéphane</ForeName>
<Initials>S</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Vincent</LastName>
<ForeName>Mireille</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>de Epidemiología</LastName>
<ForeName>Servicio</ForeName>
<Initials>S</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>General de Salud Pública Del Gover Balear</LastName>
<ForeName>Dirección</ForeName>
<Initials>D</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Masserey Spicher</LastName>
<ForeName>Virginie</ForeName>
<Initials>V</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bourquin</LastName>
<ForeName>Catherine</ForeName>
<Initials>C</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Stoll</LastName>
<ForeName>Jeanine</ForeName>
<Initials>J</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Chaud</LastName>
<ForeName>Pascal</ForeName>
<Initials>P</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Mounayar</LastName>
<ForeName>Anne-Laure</ForeName>
<Initials>AL</Initials>
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<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year>
<Month>03</Month>
<Day>05</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2020</Year>
<Month>04</Month>
<Day>09</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2020</Year>
<Month>4</Month>
<Day>12</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>8</Month>
<Day>11</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>4</Month>
<Day>12</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">32277759</ArticleId>
<ArticleId IdType="pii">5819060</ArticleId>
<ArticleId IdType="doi">10.1093/cid/ciaa424</ArticleId>
<ArticleId IdType="pmc">PMC7184384</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>France</li>
</country>
<region><li>Auvergne-Rhône-Alpes</li>
<li>Rhône-Alpes</li>
<li>Île-de-France</li>
</region>
<settlement><li>Annecy</li>
<li>Chambéry</li>
<li>Grenoble</li>
<li>Lyon</li>
<li>Paris</li>
</settlement>
<orgName><li>Université Claude Bernard Lyon 1</li>
<li>Université Grenoble-Alpes</li>
</orgName>
</list>
<tree><country name="France"><noRegion><name sortKey="Danis, Kostas" sort="Danis, Kostas" uniqKey="Danis K" first="Kostas" last="Danis">Kostas Danis</name>
</noRegion>
<name sortKey="Ader, Florence" sort="Ader, Florence" uniqKey="Ader F" first="Florence" last="Ader">Florence Ader</name>
<name sortKey="Benet, Thomas" sort="Benet, Thomas" uniqKey="Benet T" first="Thomas" last="Bénet">Thomas Bénet</name>
<name sortKey="Berra, Julien" sort="Berra, Julien" uniqKey="Berra J" first="Julien" last="Berra">Julien Berra</name>
<name sortKey="Berthelot, Philippe" sort="Berthelot, Philippe" uniqKey="Berthelot P" first="Philippe" last="Berthelot">Philippe Berthelot</name>
<name sortKey="Berthelot, Philippe" sort="Berthelot, Philippe" uniqKey="Berthelot P" first="Philippe" last="Berthelot">Philippe Berthelot</name>
<name sortKey="Botelho Nevers, Elisabeth" sort="Botelho Nevers, Elisabeth" uniqKey="Botelho Nevers E" first="Elisabeth" last="Botelho-Nevers">Elisabeth Botelho-Nevers</name>
<name sortKey="Botelho Nevers, Elisabeth" sort="Botelho Nevers, Elisabeth" uniqKey="Botelho Nevers E" first="Elisabeth" last="Botelho-Nevers">Elisabeth Botelho-Nevers</name>
<name sortKey="Boudalaa, Zoubida" sort="Boudalaa, Zoubida" uniqKey="Boudalaa Z" first="Zoubida" last="Boudalaa">Zoubida Boudalaa</name>
<name sortKey="Bouscambert Duchamp, Maude" sort="Bouscambert Duchamp, Maude" uniqKey="Bouscambert Duchamp M" first="Maude" last="Bouscambert-Duchamp">Maude Bouscambert-Duchamp</name>
<name sortKey="Campoy, Sephora" sort="Campoy, Sephora" uniqKey="Campoy S" first="Séphora" last="Campoy">Séphora Campoy</name>
<name sortKey="Chidiac, Christian" sort="Chidiac, Christian" uniqKey="Chidiac C" first="Christian" last="Chidiac">Christian Chidiac</name>
<name sortKey="Chidiac, Christian" sort="Chidiac, Christian" uniqKey="Chidiac C" first="Christian" last="Chidiac">Christian Chidiac</name>
<name sortKey="Coignard, Bruno" sort="Coignard, Bruno" uniqKey="Coignard B" first="Bruno" last="Coignard">Bruno Coignard</name>
<name sortKey="Epaulard, Olivier" sort="Epaulard, Olivier" uniqKey="Epaulard O" first="Olivier" last="Epaulard">Olivier Epaulard</name>
<name sortKey="Epaulard, Olivier" sort="Epaulard, Olivier" uniqKey="Epaulard O" first="Olivier" last="Epaulard">Olivier Epaulard</name>
<name sortKey="Epaulard, Olivier" sort="Epaulard, Olivier" uniqKey="Epaulard O" first="Olivier" last="Epaulard">Olivier Epaulard</name>
<name sortKey="Forestier, Emmanuel" sort="Forestier, Emmanuel" uniqKey="Forestier E" first="Emmanuel" last="Forestier">Emmanuel Forestier</name>
<name sortKey="Fougere, Erica" sort="Fougere, Erica" uniqKey="Fougere E" first="Erica" last="Fougere">Erica Fougere</name>
<name sortKey="Gaymard, Alexandre" sort="Gaymard, Alexandre" uniqKey="Gaymard A" first="Alexandre" last="Gaymard">Alexandre Gaymard</name>
<name sortKey="Landelle, Caroline" sort="Landelle, Caroline" uniqKey="Landelle C" first="Caroline" last="Landelle">Caroline Landelle</name>
<name sortKey="Landelle, Caroline" sort="Landelle, Caroline" uniqKey="Landelle C" first="Caroline" last="Landelle">Caroline Landelle</name>
<name sortKey="Levy Bruhl, Daniel" sort="Levy Bruhl, Daniel" uniqKey="Levy Bruhl D" first="Daniel" last="Levy-Bruhl">Daniel Levy-Bruhl</name>
<name sortKey="Lina, Bruno" sort="Lina, Bruno" uniqKey="Lina B" first="Bruno" last="Lina">Bruno Lina</name>
<name sortKey="Mailles, Alexandra" sort="Mailles, Alexandra" uniqKey="Mailles A" first="Alexandra" last="Mailles">Alexandra Mailles</name>
<name sortKey="Saura, Christine" sort="Saura, Christine" uniqKey="Saura C" first="Christine" last="Saura">Christine Saura</name>
<name sortKey="Spaccaferri, Guillaume" sort="Spaccaferri, Guillaume" uniqKey="Spaccaferri G" first="Guillaume" last="Spaccaferri">Guillaume Spaccaferri</name>
<name sortKey="Thabuis, Alexandra" sort="Thabuis, Alexandra" uniqKey="Thabuis A" first="Alexandra" last="Thabuis">Alexandra Thabuis</name>
<name sortKey="Tolsma, Violaine" sort="Tolsma, Violaine" uniqKey="Tolsma V" first="Violaine" last="Tolsma">Violaine Tolsma</name>
<name sortKey="Vaux, Sophie" sort="Vaux, Sophie" uniqKey="Vaux S" first="Sophie" last="Vaux">Sophie Vaux</name>
<name sortKey="Veil, Raphael" sort="Veil, Raphael" uniqKey="Veil R" first="Raphael" last="Veil">Raphael Veil</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/CovidFranceV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001314 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001314 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    CovidFranceV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:32277759
   |texte=   Cluster of Coronavirus Disease 2019 (COVID-19) in the French Alps, February 2020.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:32277759" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a CovidFranceV1

This area was generated with Dilib version V0.6.37.
Data generation: Tue Oct 6 23:31:36 2020. Site generation: Fri Feb 12 22:48:37 2021

	Serveur d'exploration sur la COVID en France
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur la COVID en France

Cluster of Coronavirus Disease 2019 (COVID-19) in the French Alps, February 2020.

Cluster of Coronavirus Disease 2019 (COVID-19) in the French Alps, February 2020.

Source :

Descripteurs français

English descriptors

Abstract

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Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

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